14-3-3 and its binding partners are regulators of protein–protein interactions during spermatogenesis
نویسندگان
چکیده
منابع مشابه
14-3-3 and its binding partners are regulators of protein-protein interactions during spermatogenesis.
During spermatogenesis, spermiation takes place at the adluminal edge of the seminiferous epithelium at stage VIII of the epithelial cycle during which fully developed spermatids (i.e. spermatozoa) detach from the epithelium in adult rat testes. This event coincides with the migration of preleptotene/leptotene spermatocytes across the blood-testis barrier from the basal to the apical (or adlumi...
متن کامل14-3-3 Proteins are Regulators of Autophagy
14-3-3 proteins are implicated in the regulation of proteins involved in a variety of signaling pathways. 14-3-3-dependent protein regulation occurs through phosphorylation-dependent binding that results, in many cases, in the release of survival signals in cells. Autophagy is a cell digestion process that contributes to overcoming nutrient deprivation and is initiated under stress conditions. ...
متن کاملAffinity purification of diverse plant and human 14-3-3-binding partners.
Many proteins that bind to a 14-3-3 column in competition with a 14-3-3-binding phosphopeptide have been purified from plant and mammalian cells and tissues. New 14-3-3 targets include enzymes of biosynthetic metabolism, vesicle trafficking, cell signalling and chromatin function. These findings indicate central regulatory roles for 14-3-3s in partitioning carbon among the pathways of sugar, am...
متن کامل14-3-3 proteins: a family of versatile molecular regulators.
The 14-3-3 proteins are a family of acidic regulatory molecules found in all eukaryotes. 14-3-3 proteins function as molecular scaffolds by modulating the conformation of their binding partners. Through the functional modulation of a wide range of binding partners, 14-3-3 proteins are involved in many processes, including cell cycle regulation, metabolism control, apoptosis, and control of gene...
متن کاملThe arabidopsis 14-3-3 family of signaling regulators.
The 14-3-3 family of proteins has received much attention in the literature during the last 10 years. The current interest is not surprising given the number of diverse organisms in which 14-3-3s have been identified and the important role that they play in signal transduction. Moore and Perez initially catalogued the 14-3-3 proteins in 1967 during an extensive study in which bovine brain prote...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Endocrinology
سال: 2009
ISSN: 0022-0795,1479-6805
DOI: 10.1677/joe-09-0041